ncRNA name | hsa-miR-181a-5p |
ncRNA Category | miRNA |
Disease name | primary Sjögren's syndrome (pSS) |
Species | Homo sapiens |
Tissues/Cell_line | peripheral blood mononuclear cells (PBMCs) |
Methods | microarray, qRT-PCR |
Expression pattern | up-regulated |
Functional description | In addition to the elevated miR-181a levels, our study led to the speculation that elevated miR-181a levels in the PBMC of these patients compromise the maturation of B cells, enabling them to recognize and attack autoantigens and resulting in disease phenotypes. |
PubMed ID | 25128511 |
Year | 2014 |
Title | MicroRNA profiling in Chinese patients with primary Sjögren syndrome reveals elevated miRNA-181a in peripheral blood mononuclear cells. |
Drug-related ncRNA | NO |
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