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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-181a-5p
ncRNA name hsa-miR-181a-5p
ncRNA Category miRNA
Disease name primary Sjögren's syndrome (pSS)
Species Homo sapiens
Tissues/Cell_line peripheral blood mononuclear cells (PBMCs)
Methods microarray, qRT-PCR
Expression pattern up-regulated
Functional description In addition to the elevated miR-181a levels, our study led to the speculation that elevated miR-181a levels in the PBMC of these patients compromise the maturation of B cells, enabling them to recognize and attack autoantigens and resulting in disease phenotypes.
PubMed ID 25128511
Year 2014
Title MicroRNA profiling in Chinese patients with primary Sjögren syndrome reveals elevated miRNA-181a in peripheral blood mononuclear cells.
Drug-related ncRNA NO

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